In 1929, the British Journal of Experimental Pathology received a paper from Alexander Fleming. It was on the antibacterial action of a substance named Penicillin that comes from the cultures of a Penicillium. This paper revolutionized world medicine. The Discovery of penicillin dates back to 1928 when Fleming began a series of experiment on staphylococcal bacteria. Fleming left an uncovered Petri dish near an open window. It got contaminated from outside mould spores. Later he noticed bacteria near the mould colonies were dying. He tested it against many gram-positive pathogens. It was effective in almost all. Before the discovery of penicillin, even minor cuts/wounds turned out to be fatal. Fight with pathogens and harmful viruses has been really long. Scientists and microbiologists have been studying the effects of various substances and different environments on bacteria and pathogens. This shows how important the study of antibiotics is. Here we will conduct a home lab experiment with minimum requirements to study the effects of antibiotics on bacterial culture growth.
Mainly what we will do is that we will take some slices of potato and will culture curd-bacteria (Lactobacilli) on them. Then we will test the effect of antibiotics on these bacteria, making observations and concluding with them.